Dear Friends A message from Kevin Haydon Executive Vice President & Chief Executive Officer, Philips Healthcare Global Sales & Service International + Read A brief history of X-ray diagnostics J. Hofman Philips has been involved in the development of X-ray technology for more than a century. This article presents some of the most important innovations, and their clinical applications. + Read article Non-invasive quantification and characterization of coronary plaque: the role of multidetector CT M.G. Dalager, H.E. Bøtker, M. Bøttcher, T.B. Ivanc, M.E. Olszewski and K. Norrgren Multidetector CT angiography offers a non-invasive method for evaluating the coronary arteries, while the Brilliance Workspace enables quantification and analysis of atherosclerotic plaque. + Read article Non-invasive cardiac imaging of morbidly obese patients using the Brilliance iCT scanner L. Domachevsky, T. Gaspar, N. Peled, M. Shnapp, D.A. Halon, B.S. Lewis, R. Rubinshtein, D. Hazzan, M. Vembar, and S. Samoilov The recently introduced Brilliance iCT scanner offers increased speed, power and coverage in the assessment of morbidly obese patients presenting with chest pain. + Read article Pediatric cardiology with the iE33 echocardiography system G. Tulzer The Philips iE33 echocardiography system is used for pre- and postoperative assessment of neonates and children with congenital heart disease, for evaluation of dyssynchrony and myocardial function, and for fetal echocardiography. + Read article Ultrasound-triggered image-guided therapy C. Moonen This article discusses advances in temperature- and pressure-sensitive agents for ultrasound-triggered, image-guided local drug release, and gives an overview of the potential applications of both types of delivery vehicles for different drug formats. + Read article Myocardial perfusion imaging: past, present and future J.K. O’Donnell, P. Wojtylak and P.F. Faulhaber The authors present an overview of the development of myocardial perfusion imaging, paying particular attention to the introduction of SPECT and PET, as well as the combination of the two techniques in PET-CT and SPECT-CT scanner units. + Read article Toward improving the diagnosis of Alzheimer’s Disease M.J. Sadowski, J.D. Schaffer and E. Silfen Alzheimer’s disease accounts for the majority of dementia cases with an estimated prevalence of over 25 million cases worldwide. The authors discuss current challenges in diagnosing dementia, and make the case for computer-based decision support systems. + Read article Imaging diseased vessels M. Mulligan-Kerhoe and L. Zagorchev Confocal microscopy and MicroCT are complementary techniques used in the detection of angiogenesis, which is a fundamental step in the transition of tumors from a dormant state to malignancy. This article demonstrates the use of these techniques in a mouse model. + Read article Optical imaging of the breast: clinical research using an experimental Diffuse Optical Tomography system S. van de Ven Optical breast imaging has the potential to provide biophysical and molecular information on breast tissue, making it a promising technique for breast cancer diagnosis and treatment. + Read article Summaries + Read article Technology News + Read article
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